Nick Rose scored 33 points, but Colorado College dropped its regular season finale at Hendrix College by an 88-78 count.
The Tigers were eliminated from contention for the Southern Collegiate Athletic Conference postseason tournament when Millsaps College upset Austin College.
Despite fouling out with 59 seconds remaining in the game, Rose surpassed the 30-point mark for the sixth time this season and completed his third double-double with 11 rebounds.
He finished the season with 548 points, the ninth-highest single-season total in school history. He also climbed to No. 19 in career scoring with 973 points.
Ohlsen concluded the season with 202 rebounds, No. 15 on the single-season list, and moved up to No. 6 with 549 career rebounds. His 47 blocks is the third-best single-season total, and Ohlsen is now No. 4 with 85 career rejections.
After jumping out to an early 8-4 lead, CC missed seven of its next nine shots from the floor and committed four turnovers while being outscored 20-5.
The Tigers pulled to within a point when Austin Perkins drained a three-point shot 3:52 into the second half, and the game was tied at 60 after Brady Ohlsen sank a pair of free throws with 9:05 to play.
Colorado College trailed 65-63 after Rose was fouled on a dunk and completed the three-point play with 7:29 to go. But the Warriors scored eight consecutive points to extend their lead to 10 points with 5:30 remaining and the Tigers never got closer than eight points.
CC shot only .333 from the floor in the second half, making just three of 12 field-goal attempts from inside the arc. The Tigers made seven of 18 three-point attempts during the final 20 minutes to stay within striking distance.
The Warriors were paced by Cal Rose with 23 points and Nick Heathscott with 22.
Colorado College slipped to 12-13 overall and 7-9 in the SCAC. Hendrix finished the season with a 7-17 overall record and a 4-12 mark in conference play.